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Best bets for Wednesday, October 21, 2026

Wednesday's board is almost entirely one kind of bet: NBA player props on the under. Nine of the ten top picks are unders on threes made or assists, and most of them sit at plus-money prices, meaning a winning bet pays more than it risks. The model's case is that these lines look too generous to the over. Expected profit is a long-run average across many similar bets, not a promise for any one night, and these ten picks share a lot of the same logic, so they could rise or fall together.

Desmond Bane under 1.5 threes made (+185, Bovada)

This is the top pick, with an expected profit of +$29.39 per $100. Bane needs to hit one three or none for the bet to win. It starts at 7:00 PM ET, and 720 look-alike games back it. The +185 price implies the book thinks the under hits roughly 35% of the time, and the look-alike games suggest it happens more often than that.

Aaron Nesmith under 1.5 threes made (+180, Bovada)

Same bet, different player: Nesmith stays at one three or fewer. The game starts at 8:00 PM ET, and the expected profit is +$28.69 per $100 across 555 look-alike games. A +180 price asks for the under to win only about 36% of the time to break even, so the model sees a gap.

CJ McCollum under 1.5 threes made (+175, Bovada)

McCollum rounds out the top three at +175, with an expected profit of +$26.17 per $100. The 7:00 PM ET game has 677 look-alike games behind it. Again the price seems to lean on the idea that a shooter will get hot, while the similar games say one three or fewer shows up more often than the odds suggest.

The rest of the board

Anthony Edwards under 2.5 threes (+165, Bovada) is fourth at +$24.04, with 422 look-alike games. Andrew Wiggins under 1.5 assists (+154, BetOnline.ag) follows at +$20.80 with 447. Kevin Durant under 1.5 threes (+165, Bovada) is +$19.94 on 427, and Matas Buzelis under 1.5 threes (+165, Bovada) is +$19.72 on 411. Jalen Suggs under 1.5 threes (+154, FanDuel) is the only pick not at Bovada or BetOnline.ag, at +$19.58 on 720. LaMelo Ball under 7.5 assists (+125, Bovada) is +$18.24 on 473, and Kris Dunn under 3.5 assists (+150, Bovada) closes the list at +$17.95, backed by the deepest sample of the day at 1,309 look-alike games. Prices can move before tip-off, so check that the number you see still matches.

The top 10 bets on our NBA board for Wednesday, October 21, 2026, ranked by expected profit per $100 after the sportsbook's cut. Each one is priced from how look-alike past games turned out (similar line, home or away, rest), at the best price we found across up to 11 sportsbooks.

#BetProfit per $100Result
1Desmond Bane under 1.5 threes made +185
NBA · Bovada · 720 look-alikes
+$29.39Pending
2Aaron Nesmith under 1.5 threes made +180
NBA · Bovada · 555 look-alikes
+$28.69Pending
3CJ McCollum under 1.5 threes made +175
NBA · Bovada · 677 look-alikes
+$26.17Pending
4Anthony Edwards under 2.5 threes made +165
NBA · Bovada · 422 look-alikes
+$24.04Pending
5Andrew Wiggins under 1.5 assists +154
NBA · BetOnline.ag · 447 look-alikes
+$20.80Pending
6Kevin Durant under 1.5 threes made +165
NBA · Bovada · 427 look-alikes
+$19.94Pending
7Matas Buzelis under 1.5 threes made +165
NBA · Bovada · 411 look-alikes
+$19.72Pending
8Jalen Suggs under 1.5 threes made +154
NBA · FanDuel · 720 look-alikes
+$19.58Pending
9LaMelo Ball under 7.5 assists +125
NBA · Bovada · 473 look-alikes
+$18.24Pending
10Kris Dunn under 3.5 assists +150
NBA · Bovada · 1,309 look-alikes
+$17.95Pending

Profit per $100 is the expected long-run average, not a promise: even the best edges lose often. Our full track record shows how the method has done over eight NFL seasons.

See tonight's full board